Supplement Schedule — During the SIBO Protocol

Your full stack while the IMO plan runs, with buy links. Green rows are the additions — everything else is your normal baseline, unchanged. Updated 7 August 2026.

What changes vs your baseline

Nothing is removed. Nothing moves. Zero new windows. The protocol only adds items into the two windows you already keep, plus the ~2-hrs-after-dinner micro-slot that already exists for the Motility Activator.

Phase key: P0start now   P1week 3 if P0 is partial   P2one 4-week round, then stop   P3after the round.

⏱ How long the herbs run — the one hard time limit on this plan.

  • Allicin and berberine: 4 weeks maximum, then stop. Both of them. Neither has long-term safety data, and neither has a controlled trial showing it eradicates IMO at all — a bounded single round is the whole point.
  • Do not roll straight into a second round on your own. If 4 weeks changes nothing, that is information: the answer is a clinician and a test, not another bottle.
  • Berberine may end sooner. If stools harden in the first 2 weeks, drop it there and finish the round on allicin alone.
  • Everything else on this page — MiraLAX, psyllium, Florastor, magnesium, the prokinetic — has no 4-week limit and keeps running.
WindowAddedPhaseBuy
Breakfast MiraLAX (PEG 3350) 17 gP0 — now Local pharmacies first · Amazon ~US$25
Psyllium (usual amount)P0 — now Solaray, Kellmart
Florastor 2 caps (500 mg)P1 — wk 3 if needed Amazon 100-ct (4 caps/day — skip the 50-ct)
Allicin + Berberine 500 mg — 4 weeks max, then stopP2 — 4-week round Allimax 180 / Pro 450 · Berberine HCl
Dinner Florastor 2 caps (500 mg)P1 (same bottle)
Allicin + Berberine 500 mgP2 (same bottles)
BioGaia GastrusP3 — after the round Amazon (capsule form if chewable polyols stir gas)
After-dinner micro-slot Magnesium OXIDE 400–500 mg (rides the existing slot)P1 Local pharmacies · Amazon

Off-limits while the protocol runs

⛔ While the SIBO items are running — do not take these alongside them:

  • Align, or any probiotic listing B. infantis/longum 35624 — raised breath methane in testing. Wrong strain for your type, at any phase.
  • Plain Lactobacillus/Bifidobacterium probiotics in the same swallow as the herbs — berberine/allicin kill them. Wasted, not dangerous: space 2+ hours, or hold them until Phase 3.
  • Fermentable-fiber add-ins — inulin, FOS/chicory, resistant starch, PHGG/Sunfiber, 2'-FL HMO. Feeding the thing being treated, and the trigger class.
  • Peppermint products (Atrantil, Iberogast) and concentrated oregano/thyme oils — reflux. Applies the whole way through.
  • Charcoal or any "binder" — blocks absorption of everything else on this page.
  • Extra magnesium beyond this sheet — no citrate or extra oxide on top; the oxide + glycinate pairing already sits at the ceiling.
  • Berberine + hardening stools = stop the berberine (keep allicin).
  • Surgery/dental within a week → pause omega-3, curcumin and allicin first.
  • Breath test ever booked → all probiotics off, per that lab's washout sheet.
  • Famotidine and alginates are fine — just keep MgO and psyllium ~2 hours away from famotidine when easy.

☀ Breakfast ~07:00 · green rows = protocol additions

ItemDoseHowBuy
ThiActive B1 cap≥1 hr from coffee Solaray Methyl B, Kellmart
Thiamax (TTFD)100 mgNo coffee 1 hr before → 2 hr after Objective Nutrients
L-Theanine200 mgWith/after coffee Solaray, Kellmart
Saffron (affron®)28 mgOr PS 100 mg — ONE affron · Sharp-PS
Centrum Silver Men 50+1 tabWith food pharmacies · Amazon
Vitamin D31,000 IUFattiest meal (2,000 total) pharmacies · Amazon
K2 MK-7 (opt.)50–100 mcgWith the D3 Amazon
Omega-3~1 gOther half at dinner Wiley's Finest, Kellmart
Hydroxytyrosol20 mgWith omega-3 Amazon
Polypodium (if using)240 mg Heliocare
L-Citrulline3 gShake Evlution, Kellmart
Creatine5 gShake Legion, Kellmart
CoQ10 Ubiquinol100 mgWith food Solaray, Kellmart
Curcumin Merivaper labelWith food Thorne Meriva
P0MiraLAX (PEG 3350)17 gFull glass of water local first · Amazon
P0PsylliumusualAmple water; 2 hrs from famotidine Solaray, Kellmart
P1Florastor2 capsTrial dose in active weeks Amazon 100-ct
P2Allicin (Allimax)per labelWith food. 4 weeks max, then stop Allimax 180 / Pro 450
P2Berberine HCl500 mgWith food. 4 weeks max — and drop sooner if stools harden Amazon

☾ Dinner ~22:00 · green rows = protocol additions

ItemDoseHowBuy
Borage Oil (GLA)240 mgMid-dinner Amazon
Zinc Carnosine75 mgWith/after dinner PepZin GI
Magnesium Glycinate200 mgStays — not the laxative form Source Naturals, Kellmart
Glycine3 × 1000 mgCapsules Solaray, Kellmart
L-Glutaminefull doseCapsules; doubles as recovery-phase item Evlution, Kellmart
Omega-3~1 gSecond half(same bottle)
Silexan (opt.)80 mgNot sedating Lavela WS 1265
P1Florastor2 capsSecond daily dose (same bottle)
P2Allicinper labelSecond dose, with food. 4 weeks max (same bottle)
P2Berberine HCl500 mg= 1,000 mg/day. 4 weeks max; 3rd dose only if a clinician says so (same bottle)
P3BioGaia Gastrusper labelAfter the round; one new probiotic per week Amazon

⏰ ~2 hrs after dinner the one micro-slot (already existed)

ItemDoseHowBuy
Motility Activator1–2 capsEmpty stomach, upright 15 min. This IS the P3 prokinetic — already owned; MotilPro unnecessary restock link
P1Magnesium OXIDE400–500 mg Rides the same slot — no new window. Water only local pharmacies · Amazon

As-needed (not scheduled)

Conflicts found — and how this schedule resolves them

ConflictSeverityResolution
Mg oxide stacks on Mg glycinate (~440–500 mg elemental/day combined, above the NIH 350 mg supplemental guide value) Real, managed Glycinate stays for sleep/TTFD/D; MgO takes the bedtime micro-slot. The guide value's endpoint IS diarrhea — the intended effect. Stools over-loosen → cut MgO first, never glycinate. Worth raising at the BBD$50 TeleMed consult
Berberine can cause constipation — his exact phenotype Real Hard rule: stools harden in first 2 weeks → drop berberine, keep allicin
Bleeding-watch cluster grows: omega-3 + curcumin + now allicin (berberine minor) Procedural Pre-surgery/dental: pause all three ~1 week before; mention berberine
Psyllium can slow co-swallowed absorption Minor / theoretical Fine at breakfast; only famotidine gets the 2-hr courtesy gap; minerals sit at dinner anyway
Gastrus chewable base (polyols) vs the sugar-alcohol trigger list Label flag Tiny amounts, likely fine; capsule form exists
Florastor contains a small amount of lactose Trivial Not on the trigger list; noted for completeness
PEG 3350 vs anything None found Inert and unabsorbed; no supplement interactions

No conflict by design: Florastor is a yeast — berberine and allicin cannot kill it (Maev 2025 pairing). Existing L-glutamine and zinc carnosine align with the recovery phase.

Rules that are part of the treatment

  • 4–5 hrs between meals, no snacking; ~12 hr overnight fast. The cleaning wave only runs when you are not eating.
  • Allicin + berberine stop at 4 weeks. One bounded round — no second round without a clinician. Everything else keeps running.
  • One new item at a time during P1/P2 — or the diary teaches nothing.
  • Coffee: Thiamax + B-complex at least 1 hr away.
  • Fat-solubles (D3, K2, omega-3, CoQ10, curcumin, hydroxytyrosol) with the fattiest meal.
  • Any booked breath test → all probiotics off per that lab's washout sheet.
  • B6 comes from both Centrum and ThiActive B — keep the combined total modest.